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This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD's interim permissible exposure level of 350 mg/m3Table of ContentsFront MatterSummary1 Introduction2 Dosimetry and Exposure Assessment of Jet-Propulsion Fuel 83 Toxicokinetics and Toxicodynamics of Jet-Propulsion Fuel 84 Effects of Jet-Propulsion Fuel 8 on the Respiratory Tract5 Effects of Jet-Propulsion Fuel 8 on the Nervous System6 Effects of Jet-Propulsion Fuel 8 on the Immune System7 Effects of Jet-Propulsion Fuel 8 on the Liver8 Effects of Jet-Propulsion Fuel 8 on the Kidney9 Effects of Jet-Propulsion Fuel 8 on Reproduction and Development10 Effects of Jet-Propulsion Fuel 8 on the Cardiovascular System11 Genotoxic Effects of Jet-Propulsion Fuel 812 Carcinogenic Effects of Jet-Propulsion Fuel 8Appendix A Permissible Exposure Levels for Selected Military FuelVapors: Contents and Executive Summary (NRC 1996)Appendix B JP-8 Final Risk Assessment: Contents, Executive Summary,and Introduction (TIEHH 2001)Appendix C