The role of Ca125 in clinical chemistry

Immunoradiomatric assay technique was used to measure the level of serum tumor markers CA125 and CEA in 30 healthy women, 24 patients with benign ovarian tumors and 34 patients with malignant ovarian tumors. Upon comparison of the results, the CA125 level was found above normal (35u.ml-1) in 80% of patients with ovarian cancer, while CEA level was elevated in 44% of patients with ovarian cancer (more than 3.0 u.ml-1). Among the pre-menopausal women, the values of CA125 and CEA in sera of patients with malignant ovarian tumors were found to be significantly higher (P