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Beskrivelse
The first part of this work reports the preparation of some a,ß- unsaturated carbonyl compounds which are useful as starting materials to produce new different types of heterocyclic compounds. In this part of study, we report the relation of 2-acetyl-naphthalene with some aldehydes to give the corresponding a,ß- unsaturated carbonyl compounds (Ia-c). The condensation of these compounds with some carbon and/or nitrogen nucleophiles gave the appropriate pyridine, pyrazole, oxazole derivatives. Biological activity for the synthesized compounds have been studied for anticancer evaluation, and antimicrobial activity.