The Evolution of HIV

This text brings together researchers from the disciplines of clinical research, basic molecular biology, immunology, cell biology, epidemiology, and mathematical biology to present perspectives on both the molecular biology and molecular evolution of HIV. The book is divided into three sections: "Introduction to HIV" explores the fundamentals of the virus's molecular biology in its global diversity; "Molecular Methods for Studying HIV Diversity" looks at such topics as HIV phylogenetics, modelling the molecular evolution of HIV sequences, the use of phylogenetic inference to test an HIV transmission hypothesis, and coalescent approaches to HIV population genetics; and the third section, "Case Studies of HIV Evolution" examines the levels of diversity within and among host individuals, the phylogenetics of known transmission histories, and HIV evolution and disease progression via longitudinal studies. The contributors include John M. Coffin, Esther Guzman, Edward C. Holmes, Marcia L. Kalish, Thomas Leitner, Alan R. Templeton and Gerald H. Learn.