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Sjogren's Syndrome

- Novel Insights in Pathogenic, Clinical and Therapeutic Aspects

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Sjogren's Syndrome: Novel Insights in Pathogenic, Clinical and Therapeutic Aspects provides the reader with an overview of current knowledge about Sjogren's Syndrome. The book summarizes the huge amount of literature concerning related advances in genetic background, pathogenesis, clinical picture, and therapeutic approaches. It integrates basic immunology concepts, clinical aspects, and pharmacological issues. Scientific progress has allowed us to unmask novel pathogenic mechanisms, to perform genome wide studies, and to identify clinical and serological features associated with different disease subsets and, eventually, different disease prognoses. In addition, the increasing knowledge about SS pathogenesis provides the rationale to employ targeted therapies in SS as has already occurred in rheumatoid arthritis and systemic lupus erythematosus.

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Detaljer
  • SprogEngelsk
  • Sidetal344
  • Udgivelsesdato23-06-2016
  • ISBN139780128036044
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt630 g
  • coffee cup img
    10 cm
    book img
    15,2 cm
    22,9 cm

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    History Epithelium Genetics Genomics Hormones Inflammation Management Mortality Lymphoma Infections Viruses Biological treatment B cells Tumor necrosis factor Animal models T-Lymphocytes Cytokines Pathogenesis Asia Treatment Salivary glands Therapy Autoantibodies Biologicals Environmental pollution Malt Review Epigenetics Cryoglobulinemia Environmental factors Rituximab Autoantigens Innate immunity Th17 cells HCV IL-6 FoxP3+ Sicca Cytokine Morbidity Sialadenitis Autoantibody T regulatory cells Calreticulin Abatacept Anti-B-cell treatment Autoantigen Autoimmune responses a-Fodrin Biological therapies Belimumab B-cell activating factor (BAFF)B lymphocytes B-cell activating factor (BAFF)IL-1 EULAR Sj�gren's syndrome patient-related index Elastometry Follicular T helper cells Glandular epithelia Costimulator EULAR Sj�gren's syndrome disease activity index Fodrin Germinal center IL-17 Extraglandular manifestations Lachrymal glands Muscarinic 3 receptor Germinal center (GC)Interferon (IFN)Mesenchymal stem cell (MSC) transplantation Minimally clinically important improvement Parotid swelling Primary Sj�gren's syndrome (pSS)Salivary glands IL-22 Salivary gland epithelial cells Primary Sj�gren's syndrome (pSS)Salivary gland Schirmer Test IL-21 target cells Sicca symptoms Systemic manifestations Sj�gren's syndrome Ocular staining score Mikulicz syndrome NOD mice Primary Sj�gren's syndrome Salivary Scialoscintigraphy Tumor necrosis factor (TNF)Type I interferons Ultrasonography (US)BAFF salivary flow Systemic autoimmune disease
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