Sickle Cell Disease

The most comprehensive, current sickle cell disease resource-for both clinicians and researchersA Doody's Core Title for 2023!The first and only resource of its kind, Sickle Cell Disease examines this blood disorder through both clinical and research lenses. More than 80 dedicated experts in the field present their combined clinical knowledge of basic mechanisms, screening, diagnosis, management, and treatment of myriad complex complications of a single base point mutation in the human genome. Case studies with How I Treat authoritative insights provide overviews of common and rare complications, and Key Facts offer at-a-glance high-yield information.Filled with clinical photos, illustrations, numerous original diagrams, and with free updates available online, this unmatched resource covers:Mechanisms of sickle cell diseaseHistoric and current research approachesThe latest work in gene therapy and editingGuidelines for patient care, diagnosis, unique cases, and therapiesRare and common complications, including domestic and internationally relevant topicsPsychosocial and supportive careThe newest standards of therapy and future treatment options in children and adultsCardiopulmonary complications