Rosmarinus officinalis L and Annona reticulata L

The identification of secondary metabolites in the leaves of these plants, was carried out using the general reactions of phytochemical screening. The acute and subacute hepatoprotective pharmacological profiles were evaluated in guinea pigs intoxicated with paracetamol at the dose of 500mg/kg/pc. For this purpose, several groups were formed. The control group received distilled water, the reference group was treated with Silymarin and the two experimental groups were treated with doses of 100 and 200 mg/kg/pc of the plant extracts. Biochemical markers were transaminases and bilirubins.