Role of Proteomics in High Altitude Pathophysiology

High altitude physiology is one of the ignored domain of the scientific research despite of the massive scale of the problem, suggested by nearly 24% of the global population that either visits or dwells at high altitude and remain at the risk of hypoxia associated alterations in physiology. This lecture note entitled "Role of Proteomics in High altitude Pathophysiology" is designed especially for those who are interested in learning proteomics and their application in the field of high altitude physiology. It meets the needs of the proteomics studies prescribed for the high altitude physiology as it covers pathophysiology and molecular biology of high altitude sickness, proteomics as powerful tools and major proteomic advancements on pathophysiology of acute mountain sickness.

This lecture notes has 5 units and can be completed in two sessions. Initially, we introduced the term hypobaric hypoxia as a socio-economic problem followed by the description of its pathophysiology. The later chapters describe the role of proteomics and key findings of our lab. Finally a last concluding chapter includes the future guidelines for improving the health benefits of the ongoing research and developing novel strategies for future research. Though this lecture note has been designed for the students of biology field, it would be useful also for clinical professionals in the early stage of their career. It would be helpful to anyone who desires to enhance their knowledge in the field of high altitude physiology.