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The book refer to Protein Engineering and biochemical and Immunological properties of carcinoemberyonic antigen and their receptors in mammary adenocarcinoma and benign tissues .Furthermore the evaluation of the clinical value of preoperative serum tumor markers of CA15-3 and carcinoembryonic antigen (CEA) in the diagnosis of breast cancer.Beside these amethod of immunoradiometric was developed for cytosol CEA and purificatio and identification of human CEA in metastatic tumor was carried . Then kinetic and thermodynamic wass carried out and CEA receptors were isolated and the characteristics of the binding of CEA with their receptors assay technique was used.