Mechanisms of DNA Repair

Transcription DNA repair Remodeling Regulation Protein-protein interactions Phosphorylation Chromatin Methylation Meiosis Reactive Oxygen Species Posttranslational modification Localization, RNA-POLYMERASE Posttranslational Modifications DNA mismatch repair Targeted cancer therapy ATPase Synthetic lethality Endonuclease Homologous recombination BER P53 Double-stranded DNA Single molecule ATM RSC Metal-binding proteins Nucleotide excision repair Histone methylation Ubiquitylation Histone Substrate specificity DSB Acetylation Bacterial nucleotide excision repair Base excision repair Bifunctional-DNA glycosylase Chromodomain Cell Cycle Arrest DNA jumping DSBs Cell cycle checkpoint Disordered terminal segments Double-strand break repair DNA sliding End-processing proteins Dynamic localization DNA damage recognition DNA glycosylases H3K9me3 DNA hopping INO80 Mfd Lesion recognition PCNA Holliday junction β sliding clamp Repair complexes Single-stranded DNA Structure and substrates UvrB UvrC MutL Ntg1 Single-strand breaks UvrA Tip60 Transcription-coupled repair