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Polymeric Micelles for Drug Delivery

Forfatter: info mangler
Bog
  • Format
  • Bog, paperback
  • Engelsk

Beskrivelse

Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles. Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles – such as mucosal and transdermal – and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation.

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Detaljer
  • SprogEngelsk
  • Sidetal714
  • Udgivelsesdato18-08-2022
  • ISBN139780323898683
  • Forlag Woodhead Publishing
  • FormatPaperback
Størrelse og vægt
  • Vægt1000 g
  • coffee cup img
    10 cm
    book img
    15,2 cm
    22,9 cm

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    Nanotechnology Drug targeting Inflammation Regulation Micelles Cancer vaccines Chemotherapy Animals Permeability Endocytosis Diseases Solubility Polymers Cell receptors Antibodies Immunotherapy Cell Membrane Plants Glioma Nanomedicine Self-assembly Absorption Cyclodextrin Peptide Nanocarrier Micelle Targeted cancer therapy Cytotoxicity Nanomaterials Conjugate Aptamers Applications Nanocarriers Formulations Mucoadhesion Solid tumors Nanostructure Drug-Delivery Doxorubicin Heterogeneity SiRNA Nanotoxicology Genotoxicity Polymeric micelles Diblock Copolymers Targeted Drug Delivery Hybrid Inflammatory Disease Topical drug delivery SiRNA Delivery Biopolymer Nanopharmaceuticals EPR effect Safety-by-Design Gastrointestinal Nanoformulation ABC triblock copolymer Biopharmaceutical Classification System Cleavable links Cellular uptake mechanism Chimeric antigen receptor–expressing T cells Covalent conjugation Critical micelle concentration (CMC) Epithelial barriers EPR enhancement Enzyme responsiveness Checkpoint inhibitors Drugs codelivery Dual polymeric micelles Environmental Hazard Critical micellar concentration Dermal topical drug administration Drug loading Exogenous stimuli Light-responsive Nonbiological complex drugs Ocular topical drug administration Functionalized polymeric micelles PH-responsive drugs release Polymer types Receptor-mediated endocytosis Polyethylacrylate Polymer Micelles Self-assembling Subcutaneous drug delivery Targeting ligands Triblock Copolymers Tumor-targeting ligands Thermoresponsive drug release uptake Nose-to-brain delivery oral drug delivery Polymeric micelle Smart Nanomaterials
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