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- NEW! The Bigger Picture bulleted summaries identify other body systems that might be affected by a particular disease or disorder covered in a body system chapter. - NEW coverage of COVID-19 is added, as well as new information on other conditions and diseases. - NEW diagnostic methods and treatments are covered, describing how these are impacted by digitalization, information technology, and artificial intelligence. - NEW! Updated statistics on diseases and their related pathophysiology are included. - NEW photographs and illustrations are added.