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This issue of Neurologic Clinics, edited by Dr. Alejandro A. Rabinstein, will cover Neurocritical Care. Topics include, but are not limited to: Anoxic Brain Injury; Treatment of Intracranial Hypertension; Management of Traumatic Brain Injury; Cortical Spreading Depression and Ischemia in Neurocritical Patients; Temperature Control in Acute Brain Injury; HSV Encephalitis; Primary Acute Neuromuscular Respiratory Failure; ICU-Acquired Weakness; Emergency and Critical Care Management of Intracerebral Hemorrhage; New developments in Refractory Status Epilepticus; Acute Cardiac Complications in Critical Brain Disease; Nosocomial Infections in Neurocritical Patients; Neurological Complications after Solid Organ Transplantation; and Shared Decision Making in the NICU.