Na Channels from Phyla to Function

15 Snake Intelligence Epilepsy Adaptation Inflammation Information theory Ion channels Molecular dynamics. Local anesthetics Ischemia Toxins Potassium channels Cell migration Computer simulation Mutagenesis Bacteria Membrane proteins Adaptations Electrophysiology Sensory neurons Lipids Tetrodotoxin Cholesterol Arrhythmia Pain Vitalism Kinetics Fatty acids Conduction Sodium channels Phospholipids Transient Receptor Potential Channels Trauma Pyrethroids Sphingolipids Salamander History of science Phylogenetic analysis Channelopathies Structure and function Kinetic processes Compensation Selectivity Free Energy Methods Cardiac arrhythmia Drug binding Epistasis NAV Molecular dynamics simulation Neuropathic Voltage sensing Sodium channel Voltage Clamp Keyword Cell adhesion molecule Ion homeostasis Permeation Action potential Excitotoxicity Mechanosensitivity Neurite outgrowth Gating SCN5A Homology Modeling Voltage-gated sodium channel Inactivation Acquired sodium channelopathy Axon initial segment Beta subunit Arms race coevolution Channel blockers Channel activators Auxiliary subunits BDF 9148 Axon pathfinding Batrachotoxin Bleb Cell shortening Conotoxins Channelome Direct coupling analysis Fast inactivation Fibroblast growth factor homologous factor Gating modifier Immunoglobulin superfamily Inner vestibule Hyperpolarizing shift Dravet syndrome Ion permeation Inactivation gate Ion channel pharmacology Ligand docking Nodes of Ranvier Genetic and genomic background Na Channel Genotype-phenotype variability Na+ current Pore blocker Outer vestibule Resurgent currents Late Na+ current Ion conduction Selectivity filter Sodium selectivity Site 8 Voltage-gated sodium channels Site 1 Site 4 Ventricular Myocyte Voltage Dependence Membrane damage Translational modifiers Voltage-gated potassium channels voltage-gated ion channel Palmitoylation Posttranslational modifiers Sick excitable cells Slow inactivation Site 6 Ultraslow inactivation Transcriptional modifiers