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Until now, the nature and causes of depression were a mystery, and effective treatment was elusive. This story changes that. Psychotherapist and meditation teacher Michael Masani draws on cutting edge neuroscience and 30 years of clinical practice to explain how anxiety causes the neurological dysfunction that is depression. We learn how anxiety affects the nervous system, leading to a state of hyper-connectivity or 'the mind that can't let go.' These and other crucial discoveries are revealed in the true story of Darren. Darren has suffered from major depression and anxiety for over 18 years. Talk therapy, anti-depressants and electric shock therapy have not helped his condition. His illness is severe and long lasting. After all mainstream treatments have failed, Darren's psychiatrist refers him to see Michael. Michael is taking psychotherapy in a new direction, engaging directly with the subconscious mind using voice-guided meditation, story and pattern recognition. As Michael explains, healing is a function of the emotional brain and occurs within the subconscious realms.