G Protein Coupled Receptors

Evolution Inflammation X-ray crystallography Mutagenesis Membrane proteins Structure Purification Multidimensional scaling OPTIMIZATION X-ray Pichia pastoris Purines Variants Alternative Splicing Pyrimidines G-Protein Coupled Receptor Protein production Membrane Protein MRNA PCR High-throughput Structure Determination Crystal structure Protein structure prediction Molecular modeling G protein-coupled receptors Affinity purification VIP Binding site Molecular dynamics simulation GPCRs Ligand binding Antagonist GPCR Sequence space Homology Modeling adenosine A2A receptor adrenergic receptor CRH-R1 Cholesteryl hemisuccinate Expression system Conformational energy landscape heterologous expression system Insect cell expression Interaction partner Metabotropic Glutamate Receptor mGluR mGlu receptor functional selectivity Protein phosphatase 1 Receptor activation Isoforms Ligand binding mode Seven-transmembrane receptors T4 lysozyme Membrane protein stabilization Neoceptor Photolabeling ZM241385 VPAC1