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The Functional Food Center has held 28 successful International Conferences, including this one, since 2004. We take special interest in enabling the assimilation of scientific knowledge at our conferences under the series "Functional Foods and Chronic Diseases: Science and Practice." The 28th International Conference was held on August 28th to August 29th, 2020 virtually this year. This conference was titled "Functional and Healthy Foods for Longevity: Bioactive Compounds and Biomarkers in Age-Related Diseases"Main conference sessions include:Session 1. Opening and Keynote Session. Session 2: Nutritional Support for Fighting COVID-19Session 3: Enhancing the Elderly's Immune System to Fight Chronic and Viral DiseasesSession 4. Diet, Nutrition and Functional Foods for Older Adults Session 5. Prebiotics, Probiotics, Microbiota, and Healthy Aging Session 6: Functional Foods and Bioactive Compounds for Disease Management and Healthy Aging Session 7: Functional Ingredients/Bioactive Compounds and Healthy Aging Session 8: Biomarkers and Bioactive Compounds and Chronic Diseases Management: Anti-Aging Strategies Session 9: Functional Foods: Definition, Regulations in Japan and USAPosters Sessions and Exhibition Sessions were held at the end of each day. Presented in this book are scientists, food manufacturers, and healthcare professionals who are committed to functional food research. They have brought together ideas and research to prevent and manage chronic illnesses in order to improve quality of life through the utilization of functional foods with bioactive compounds.