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Beskrivelse
This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively.- Use of preclinical and early clinical data for accelerating antimicrobial drug development- Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs- Scope and limitations on the potent antimicrobial activities of hydrazone derivatives- Current scenario of anti-leishmanial drugs and treatment- Dengue hemorrhagic fever: the potential repurposing drugs