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Essentials of Antimicrobial Stewardship

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  • Format
  • Bog, paperback
  • Engelsk
  • 876 sider

Beskrivelse

Section 1: Core Components of Antimicrobial Stewardship

1. Introduction to Antimicrobial Stewardship

2. Implementation of Antimicrobial Stewardship Program

2.1. Core Elements of AMS Program

2.2. Steps of Implementation of AMS Program in a Hospital

2.3. Role of Information Technology in AMS Program

2.4. AMS Interventions

2.5. Role of Behavioral Change in AMS

3. Monitoring of Antimicrobial Stewardship

4. Current Scenario of Antimicrobial Resistance and Role of AMR Surveillance



Section 2: Diagnostic Stewardship



5. Introduction to Diagnostic Stewardship

6. Role of Appropriate Specimen Collection

7. Role of Direct Microscopy

8. Accurate Processing of Clinical Specimens and Reporting of Cultures

9. Role of Accurate Microbial Identification

10. Basics of Antimicrobial Susceptibility Testing

11. Interpretation of Antimicrobial Susceptibility Testing

12. Detection of Specific Antimicrobial Resistance

13. Quality Control in Antimicrobial Susceptibility Testing

14. Direct Susceptibility Testing

15. Selective Reporting and Role of Breakpoint-to-MIC Quotient

16. Comments in Clinical Microbiology Reporting

17. Role of Biomarkers and Point-of-care Tests (POCT) in AMS



Section 3: Hospital Antibiogram



18. Introduction to Antibiogram

19. Routine Antibiogram

20. Specialized Antibiograms

21. Use of Antibiogram

22. Analysis of MDR/XDR/PDR Phenotypes



Section 4: Antimicrobial Agents



23. Antimicrobial Agents: Classification and PK-PD Considerations

24. Cell Wall Active Agents-I: B-lactams

25. Cell Wall Active Agents-II: Glycopeptides and Fosfomycins

26. Cell Membrane Acting Agents: Polymyxins and Daptomycin

27. Protein Synthesis Inhibitors: Aminoglycosides, Tetracyclines, Glycylcyclines, Macrolides, Lincosamides, Oxazolidinones, Streptogramins, Chloramphenicol and Others

28. Nucleic Acid, Folic Acid Synthesis Inhibitors and Others: Quinolones, Nitroimidazoles, Nitrofurans,

Cotrimoxazole and Topical Agents

29. Antitubercular Drugs and Treatment Guidelines

30. Antiviral Drugs

31. Antifungal Drugs

32. Antiparasitic Drugs



Section 5: Antimicrobial Therapy (Clinical Stewardship)



33. Empirical Antimicrobial Therapy

33.1. Cardiovascular Infections

33.2. Sepsis and Bloodstream Infections

33.3. Central Nervous System Infections

33.4. Intra-abdominal Infections

33.5. Skin and Soft Tissue Infections

33.6. Respiratory Tract Infections

33.7. Genito-urinary Tract Infections

33.8. Bone and Joint Infections

33.9. Post-cardiovascular Surgery Infections

33.10. Ocular Infections

33.11. Ear Infections

33.12. Burn Wound Infections

33.13. Antimicrobial Policy in Febrile Neutropenia

33.14. Infections in Solid Organ Transplant Recipients (Non-neutropenic Settings)

33.15. Pediatric Infections

33.16. Neonatal Infections

34. Targeted Antimicrobial Therapy for Gram-positive Bacterial Infections

35. Targeted Antimicrobial Therapy for Gram-negative Bacterial Infections

36. Antifungal Stewardship and Treatment of Fungal Infections

37. Antimicrobial Prophylaxis



Section 6: Miscellaneous



38. Antimicrobial Stewardship in Special Situations

38.1. AMS in Outpatient Setting

38.2. AMS in Outpatient Parenteral Antimicrobial Therapy (OPAT) Settings

38.3. AMS in Long-term Care Facility Setting

38.4. AMS in Critical Care Units

38.5. AMS in Immunocompromised Patients

38.6. AMS in Pediatric Units

38.7. AMS in Community Hospitals

39. One Health Approach in Antimicrobial Stewardship

40. Hospital Sou

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