Epigenetics in Human Disease

- Volume 6

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Epigenetics in Human Disease, Second Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, and epigenetic mechanisms of imprinting disorders. Further sections explore online epigenetic tools and datasets, early-life programming of epigenetics in age-related diseases, the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies.

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Detaljer
  • SprogEngelsk
  • Sidetal1110
  • Udgivelsesdato18-05-2018
  • ISBN139780128122150
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt2450 g
  • coffee cup img
    10 cm
    book img
    19,1 cm
    23,5 cm

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    Diabetes Insulin Obesity Cancer Children Asthma Infertility Embryo Nutrition Aging Disease Adaptation Epidemiology Inflammation Insulin resistance. Management Mortality Cardiovascular Diseases Prevention Germ cells Neuroplasticity Endometriosis Parkinson's disease Eczema Endometrium Infection Systemic lupus erythematosus Animal models Food allergy Etiology Genomic imprinting Public health Stem cells MicroRNAs Treatment Histone deacetylase Embryonic stem cells Rheumatoid arthritis Human reproduction Chromatin Sepsis Ovarian cancer Bioinformatics Inhibitors Amyotrophic lateral sclerosis Methylation Adults Antisense RNA Glucose Huntington's Disease DNA Methylation Leiomyoma Induced Pluripotent Stem Cells Pluripotent Stem Cells Epigenetics Alternative Splicing Intellectual Disability Neurogenesis asd Alzheimer's disease Breast cancer MicroRNA Autoimmune disease Exosomes Human Cellular Reprogramming Transgenerational inheritance Histone acetylation Autoimmune Imprinting Chromatin modification Epigenomic Type 2 diabetes Endometrial Cancer Epigenome Long noncoding RNA Developmental programming Risk prediction Oncogene LncRNA Noncoding RNA Environmental stimuli Human disease Epigenetic Therapeutic Histone modifications Cervical Cancer Glycemic traits Intrauterine growth restriction Histone modification Epigenome-wide association studies Study design Small molecule inhibitors Allergic rhinitis PCOS Genome stability Neurodegeneration Hypermethylation Noncoding RNAs Aging-Related Disease Histone deacetylases Biomarker NGS Histone methylation Small molecules MiRNA Histone Innate immune response Autoantibody Causal inference ChIP-Seq Non-coding RNAs Systemic sclerosis Adaptive immune response Gene regulation Genomic disorders NcRNAs Polymorphism Regulatory T Cell DNA methyltransferase Biological age HDACi Acetyltransferases Age acceleration Assisted reproductive technology (ART)DNA methylation Autoreactive lymphocyte Antisense Drugs ATAC-seq Bacterial effector Central tolerance BET proteins Chromatin bivalency BS-Seq Chromosome band CpG islands (CGIs)DNA methylation Candidate gene studies DNMT Environmental stressor DNA hydroxymethylation Disease Risk Circular RNA (circRNA)DNA methylation DNA methyltransferase (DNMT)Epigenetic therapy Epidrugs Epigenetic therapy Epigenetic diseases Epigenetic clock CpG methylation Higher order chromatin organization Histone acetylases Immunological self-tolerance Histone ubiquitination Histone demethylase DNA Replication Timing Hypomethylation Dynamic epigenome Epigenetic reprogramming Epimutation Mitochondrial epigenetics Lamina-associated domain Genomic rearrangement neurodevelopmental disorder Metastable epialleles Nuclear morphology Hi-C Histone acetyltransferase Histone phosphorylation Neurobiological disorders Histone tail modifications Pathoepigenetics Primary biliary cholangitis or cirrhosis Peripheral tolerance RNA transcripts Histone Code Histone methyltransferase Human cancer Intergenerational inheritance Islets Small ribonucleic acid Tumor suppressor gene (TSG)Type 1 diabetes Long noncoding RNA (lncRNA)MicroRNA (miRNA)Neurobehavior Next-generation sequencing (NGS)R/G-chromosomal band boundary Self-antigen Perspective therapy Viral oncoptotein

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