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Epigenetic Cancer Therapy

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver). The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.

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Detaljer
  • SprogEngelsk
  • Sidetal748
  • Udgivelsesdato24-08-2015
  • ISBN139780128002063
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt1720 g
  • coffee cup img
    10 cm
    book img
    19,1 cm
    23,5 cm

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    Cancer Leukemia Cisplatin Classification Clinical trials Diagnosis Lymphoma Glioblastoma DNA damage Chemotherapy Histone deacetylase Apoptosis Inhibitors DNA Methylation Epigenetics Early detection Hedgehog Breast cancer Comparative epigenomics Histone acetylation Demethylation Esophageal cancer Long noncoding RNA Function Androgen Receptor Gene transcription Epigenetic Histone modifications Homologous recombination Cancer stem cell Kinases Endoplasmic reticulum stress Histone modification HDAC inhibitor Enzyme Castration resistant prostate cancer Hypermethylation Histone deacetylases Epigenetic regulation Liver cancer Biomarker Drug response Dietary intervention Histone Cancer therapy Gene regulation Cancer genetics EAC DNA methyltransferase EZH2 Acetylation Dnmt1 Acetylome AntagomiR AntimiR Base excision repair BRD7 Cancer evolution cancer epigenetics Cancer prevention and therapy Computational epigenetics Chemosensitization DNA methyltransferases DNMT Bromodomains Epigenetic enzyme Epigenetic code Epigenetic databases DNA hydroxymethylation Double-strand break repair CSC targeting Epigenetic therapy Epigenomic tools Epi-miRNA Evolutionary trajectory Epigenomic data analysis EPZ6348 Epigenetic modifiers CpG islands GSK126 HDAC Histone demethylase DNMT inhibitor Histone Deacetylase Inhibitors Enzymatic inhibitors Epigenetic drugs Epigenetic target Intratumoral heterogeneity Isocitrate dehydrogenases 1 and 2 ESCC Lnc-BCL2L11-3 Fibrillarin Histone acetyltransferase Hypomethylating agent Histone Code Intratumor heterogeneity
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