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Ecology and Evolution of Cancer

Forfatter: info mangler
Bog
  • Format
  • Bog, paperback
  • Engelsk

Beskrivelse

Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures.

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Detaljer
  • SprogEngelsk
  • Sidetal290
  • Udgivelsesdato14-02-2017
  • ISBN139780128043103
  • Forlag Academic Press Inc
  • FormatPaperback
Størrelse og vægt
  • Vægt810 g
  • coffee cup img
    10 cm
    book img
    21,6 cm
    27,6 cm

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    Fitness Sex Evolution Cancer Competition Resistance Adaptation Ecology Invertebrates Mortality Resource allocation Plasticity Infection Homeostasis Bacteria Animal behavior Magnetic resonance imaging Heat shock proteins Metastasis Selection Amphibians Oncology Immunotherapy Dormancy Neoplasia Phenotypic plasticity Primitive DNA Methylation Invasion Epigenetics Oncogenesis Life history theory Innate T cells Ecosystem functioning Malignant Hypoxia Noncoding RNA Acidity Angiogenesis Population Heterogeneity Stroma Community structure Targeted Therapies Avian Histone modification Morbidity Paradigm Cooperative System Commonality Immune cells Genome instability Microenvironment Double-bind theory Primeval adaptive therapy antivirulence Antagonistic Pleiotropy cancer defense cancer treatment response chromosomal instability cancer prevalence and etiology comparative oncology competitive release CA-IX Clonal evolution canine transmissible venereal tumor disseminated neoplasia of bivalves genome-mediated macrocellular evolution evolutionarily coupled treatment G×E genomic landscape of cancer cooption Genome chaos life-history traits Malignant phenotype life-history phases lineage selection Niche engineering miniaturized species fuzzy inheritance non-Darwinian evolution nuclear topography Primary tumor GLUT-1 Pseudohypoxia predator facilitation reversible quiescence life history trade-offs resistance to cancer therapy selfish mutants Intratumor heterogeneity metastatic tumor MHC class I-like genes multistage carcinogenesis Peto's paradox survival landscape system inheritance punctuated cancer evolution somatic conflict
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