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Grizzled Gulf War veteran turned truck driver Jack Hammers reluctantly enlists the aid of a streetwise prostitute Chrystalline to rescue his son from Jack's sleazy pimp brother who's also a security guard. After reluctantly stopping at the Get Em N Go. Eventually he finds himself teamed up with Chrystalline to battle intergalactic evil aliens and spoil their plan to overtake earth.
...A trio of reptilian aliens have crash-landed on Earth just outside of the Get Em N Go truck stop. After observing the behavior of lot lizards in their natural habitat, the aliens morph into prostitutes in order to extract semen from truckers to refuel their spaceship and return to their home planet Zenotho. The only drawback to their plan is that after extracting the semen, the truckers literally shrivel up and die. When the aliens underestimate the grit and toughness of Jack and Chrystalline, they call for a special force alien team from their home planet to engage in an all-out war with the earthlings.
...As if everything going down at the Get Em N Go wasn't enough, a ragtag duo of oversexed and violence-prone men in black operatives tracking the same alien crash landing to the very same truck stop. As soon as they arrive, things go from bad to way, way worse.