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Bone Cancer

- Bone Sarcomas and Bone Metastases From Bench to Bedside

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, Third Edition comprehensively investigates key discoveries in the field of bone biology. New aspects of bone cancer biology are treated in new chapters covering exosomes, autophagy, and metabolism. These have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches.  The Third Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with 40% new material. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases. This revision opens the door to myeloma with two short chapters dedicated to this bone-associated disease.

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Detaljer
  • SprogEngelsk
  • Sidetal1078
  • Udgivelsesdato22-09-2021
  • ISBN139780128216668
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt3040 g
  • coffee cup img
    10 cm
    book img
    21,6 cm
    27,6 cm

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    Cancer Amputation Model Classification Clinical trials Diagnosis Genetics Computer algorithms Monitoring Medical imaging Breast Bone remodeling Machine learning Diagnostic imaging Analgesia Multiple myeloma Metabolites Imaging Limb salvage Animal models Cytokines Ewing's sarcoma Chemotherapy Biopsy Bone metastasis Neoplasm Metastasis Metastasis Macrophages Growth factors Cytogenetics Extracellular matrix Apoptosis Bone marrow Histopathology Bone Neoplasms Immunotherapy Bone Autophagy Brachytherapy Carcinoma Dormancy Epiphysis Osteoclasts Epigenetics Immunomodulation Genomic Instability Giant Cell Tumor of Bone Genome-Wide Association Study economy Artificial intelligence Breast cancer MicroRNA Exosomes Immune suppression Bone sarcoma Next generation sequencing CT Microfluidic Bone targeted agents Epigenome Liquid biopsy Cancer genomics Clinical application In vivo models Beta-Blockers Convolutional Neural Networks Hypoxia Ewing sarcoma Metastases Cancer stem cells Molecular diagnostics Immune regulation MTOR inhibitors Osteoblast Bone cancer Biomarkers Myeloma Epithelial-mesenchymal transition Angiogenesis Extracellular vesicles GAP junction Bone disease Childhood cancer Bisphosphonate Cancer stem cell Necroptosis Margins Disseminated tumor cells EVs Musculoskeletal Malignant neoplasms Chromosomal abnormalities Chemoresistance Adipocytes Chondroblastoma Bone sarcomas Multidisciplinary approach Chordoma Bone Tumors Bisphosphonates Denosumab Circulating Tumor Cells Bone metabolism Chondrosarcoma Deep learning: Hadrontherapy Aromatase inhibitors Bone metastases Epigenetic aberrations MiRNA Cancer therapy Immune cells Microvesicles Oncoproteins Microenvironment Drug target Osteoblasts Osteolysis Bone Turnover Markers Osteocytes Chondrosarcomas Niche Histomorphometry Osteochondroma Disease Monitoring Acid-sensing ion channels Acridine Orange Angiogenic dormancy Antiangiogenic agents ATRAID Anti-HER-2 drugs AppCp Bone microenvironment Bone-targeted treatments Bone Cancer Pain Bone metastases complications Bone staining Cancer cell dormancy Carbonic Anhydrase IX Aurora kinase inhibitors Bloom syndrome Bone embedding Clinical implications of tumor heterogeneity Chromosomal alterations Cancer-induced bone pain Clonal evolution CB1CB2Endocannabinoid Cdk inhibitors Central Sensitization Bone-active agents Bone neoplasm Bone-seeking radiopharmaceuticals CD4/6 inhibitors Cancer-induced osteolysis Castrate-resistant prostate cancer (CRPC)Prostate cancer Energetic metabolism and reprogramming signaling Disseminating tumor cells Extracellular cell matrix Feedforward cycle Epigenetic inhibitors EWS-FLI1Primitive neuroectodermal tumor Dormancy models Giant tumor cell of the bone Connexin43Ewing's sarcoma Enneking classification Epigenetic therapies EWSR1-FLI1EGR2GGAA microsatellites Deletions Goldner trichrome Histone mutation Guanine nucleotide-binding protein/a-subunit Hypervascular tumors Ibandronate Immunogenic dormancy Epigenetic heterogeneity Inflammatory profile Ewing sarcoma model EXT1EXT2Giant cell Isocitrate dehydrogenase Metastatasis Lung Cancer Ewing's sarcomas Fibro-osseous benign lesions Mouse double minute 2MRI micro-computed tomography Flare phenomenon Long noncoding RNA (lncRNA)Osteosarcoma Fusion genes Metastasis-associated macrophages Methylmethacrylate embedding NF-?B Musculoskeletal sarcoma Hypoxia-inducible factor (HIF)Immune profile Osteoimmunology Immune microenvironment IGF1Mesenchymal stem cell Intratumoral acidosis Intratumor heterogeneity Mifamurtide Malignant giant cell tumor of bone (GCTB)Osteosarcoma Metastatic niche Low-grade osteosarcomas Novel bone-targeted therapies Osteochondroma: Sarcoma Osteoclast Osteocyte Multiple osteochondromas Osteomimicry hallmarks
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