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Biomaterials Associated Infection

- Immunological Aspects and Antimicrobial Strategies

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function.  These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.



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23,5 cm

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Staphylococcus aureus Antimicrobial-Modified Vascular Catheters Antimicrobial biomaterials Anti-infective material Intracellular bacteria Anti-adhesive and Antibacterial Polymer Brushes Antibiotic coating device Staphylococcus epidermidis Biomaterial dendritic cell interactions Dendritic cell-biomaterial interactions Implant associated infection Antimicrobial device Coagulase negative staphylococci infection Antimicrobial coating device Antibacterial biomaterials Colonization of tissue surrounding inserted medical devices Antibiotic release BAI biofilm formation biomaterial biomaterial implanted biomaterials immunology biomaterial antimicrobials Foreign body response Medical device associated infection Preventive Strategies in VAP Propionibacterium acnes Peri-implant tissue colonization indwelling bladder catheter indwelling bladder catheter infection immune response implanted Quaternary Ammonium Compounds Staphylococcus aureus infection of implanted medical devices Staphylococcus epidermidis infection of inserted medical devices Staphylococcus epidermidis medical device associated infection S. epidermidis/ S. aureus biofilm Staphylococcus aureus implant associated infection immune function implanted biomaterial tissue colonisation in BAI Infection of inserted or implanted medical devices Silver containing biomaterials race for the surface S. epidermidis biofilm interactions tissue infection Peri-implantitis biofilm Rifampin biofilm Staphylococcal virulence factors Staphylococcus aureus medical device associated infection Staphylococcus epidermidis implant associated infection
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