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As stated in the preface to the first edition, this book is intended to be a review and not a comprehensive textbook of Biochemistry and Molecular Biology. The book covers only the highlights from the much more detailed knowledge that is usually found in textbooks and we recommend that the reader turn to several excellent texts for more detailed reference. The book is intended to help those who are studying for National Medical Board Examinations and for similar ex- aminations in the Allied Health fields. Although there is now a new form of unified medical examination, NMSLE Stage 1, the basic knowledge required to pass the biochemistry portion of this examination has not changed to any marked degree. Two new chapters have been included that were not present in the first edi- tion: Membranes and a chapter on Recombinant DNA Technology as related to medicine. The chapter on Genetic Diseases has been discontinued with the genetic now dispersed through the individual chapters information previously covered where appropriate. Each chapter has been carefully revised and rewritten where necessary and updated with the advent of new information. We have changed the question types that are included at the end of each chapter to conform more closely to the format now used in NMSLE examinations. As a general rule, words or other concepts which we consider to be of special importance have been por- trayed in bold type, significant enzymes are in italics.