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Autophagy and Cardiometabolic Diseases

- From Molecular Mechanisms to Translational Medicine

  • Format
  • Bog, paperback
  • Engelsk

Beskrivelse

Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners.

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Detaljer
  • SprogEngelsk
  • Sidetal340
  • Udgivelsesdato14-04-2018
  • ISBN139780128052532
  • Forlag Academic Press Inc
  • FormatPaperback
Størrelse og vægt
  • Vægt1090 g
  • coffee cup img
    10 cm
    book img
    21,6 cm
    27,6 cm

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    Diabetes Er Obesity Heart Circadian rhythm Diabetes mellitus Hypertension Insulin resistance. Cardiovascular Diseases Ischemia Pharmacology Pulmonary hypertension Parkinson's disease Fasting Macrophage Quality control Metabolic syndrome Atherosclerosis Fibrosis Oxidative stress Cirrhosis Diseases Preeclampsia Sepsis Mitochondria Placenta Hypertrophy Apoptosis Heart failure Autophagy Endothelial Cells Glucose Huntington's Disease Method Lipid Metabolism Sirtuins Alzheimer's disease Reactive Oxygen Species SNAREs Macroautophagy PI3K Dyslipidemia Cardiomyopathy Stress response Steatosis Cardiovascular Tumor metabolism Gestational diabetes Nutrient sensing Quantification Smooth Muscle Cells Cardiac aging Protein quality control High-fat diet Translational medicine Tumor metastasis Mitochondrial Biogenesis Therapeutic Cardio-metabolic syndrome Cardiometabolic disease Kidney Disease PKB ER stress HCC Lysosome Ischemic stroke AMPK PCOS Muscle hypertrophy Neurodegeneration Cardiac Mitophagy Endurance Exercise Epigenetic regulation Cardiac Disease Amino acid Proteostasis Cardiac remodeling Ubiquitylation MTOR Maternal obesity Hemorrhagic stroke Fatty acid Autophagosome Acetylation Autophagy inhibition Antineoplastic agents/drug effects/autophagy targeted therapy Autophagy induction Autophagy flux Chaperone-mediated autophagy Autophagy addiction/KRAS/BRAF-driven cancers Cardiometabolic diseases Cardiometabolic syndrome Cargo Recognition cellular homeostasis Fetal or developmental programming Forkhead Defective autophagy Glycophagy Hypertensive Heart Disease Experiment models FoxO Maternal Undernutrition Resistance Exercise Triacylglycerol Lipophagy LAMP-2A Tumor resistance Tumor relapse TFEB Skeletal muscle tumor dormancy
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