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Ascaris

- The Neglected Parasite

Forfatter: info mangler
Bog
  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines.Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites.

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Detaljer
  • SprogEngelsk
  • Sidetal460
  • Udgivelsesdato02-08-2013
  • ISBN139780123969781
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt860 g
  • coffee cup img
    10 cm
    book img
    15,2 cm
    22,9 cm

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    Evolution Vaccination Hepatitis Malaria Asthma Tuberculosis Disease Transmission Allergy Diagnosis Genome Mathematical models Mortality Pigs Immune response Gastrointestinal Tract Pathology Hybridization Allergens Electrophysiology Cytokines Control Statistical models Liver Treatment Pathogenicity Molecular epidemiology Population genetics Lungs Bioinformatics Farm management Immunogenetics Ascariasis Humans Population Dynamics Protein Structure Respiratory syncytial virus Immunomodulation Transcriptome G-Protein Coupled Receptor Inbred mouse strains Drug efficacy Treatment Effects Co-infection Parasite Drug targets Neuropeptide Heritability Mass drug administration Pedigree analysis Heterogeneity Taxonomy Human Immunodeficiency Virus Immunobiology Phylogenetics Atopy Disease burden IgE DNA barcoding Mathematical modeling, Diagnostic methods Monitoring and Evaluation Neurotransmitter Transmission dynamics Massively Parallel Sequencing ABA-1 anthelmintic antigen polymorphism anthelmintics Ascaris Suum As-p18 C57BL/6j Clinical disease Clinical effects CBA/Ca bounce-back times Effective Population Size Density Dependence experimental infections FMRFamide-like peptide hepatic immunology host genetic factors Landscape Genetics Ligand-gated ion channel milk spots localized infection numbers infected Neuromodulator parasite genotypes quantitative trait locus (QTL) reservoir hosts preventive chemotherapy reproduction number resistance/susceptibility Systemic infection Th1 Immunoregulatory ligand-gated chloride channel larval migration school-based de-worming neuropeptide-like protein Th2 white spot formation transmission limits
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