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AM:STARs: Adolescent Medicine: State of the Art Reviews is the official publication of the American Academy of Pediatrics Section on Adolescent Health. Published 3 times per year, the journal offers adolescent medicine specialists and other primary care physicians who treat adolescent patients with state of the art information on all matters relating to adolescent health and wellness.Substance abuse continues to be a significant health problem for adolescents and young adults in the United States and elsewhere. Up-to-date information on the many facets of this issue is essential for physicians who care for these young people. This issue provides reviews of the latest information on the various substances that adolescents use and how they use them. Articles ranging from overviews of current use of data to facts about specific substances such as alcohol, marijuana, prescription stimulants, and opioids, use by different cultural groups, and various treatment options give an extensive and authoritative view of this significant adolescent health issue.Contents include: Adolescent Substance Use: The Role of the Medical Home Neurobiology of Adolescent Substance Use and Addictive Behaviors: Treatment Implications Marijuana Nonmedical Use of Prescription Stimulants by Adolescents Responding to the Prescription Opioid Epidemic: Practical Information of Pediatricians Performance-Enhancing Substances Screening and Brief Intervention for Alcohol and Other Abuse Treatment of Adolescent Substance Abuse Disorders Substance Abuse Among Culturally Diverse Youth Evolving Array of Substance use by Adolescents Assessment and Treatment of Substance Abuse in the Juvenile Justice Population