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Behind every great man is a great woman...? Maybe so, but the women in Sherlock Holmes's life are tired of toiling in his shadow. Matters come to a head when the Great Man declines to help a desperate young bride, prompting Mrs. Hudson (Holmes's housekeeper) and Mary Watson (wife to the good Doctor) to set up a sleuthing shop of their own, operating out of the kitchen at 221B Baker Street. Every clue they untangle leads to, yes, the grim slums of Whitechapel, where Jack the Ripper appears still to be busy with his carving knives. The shadow of evil looms much larger than Mary and Mrs. Hudson imagined when they hatched their plans at the kitchen table. But with so many women in terrible danger, it seems only appropriate that it's women who will set things right.