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    Target Organ Toxicity, Volume I

    Target Organ Toxicity, Volume I

    - v. 1

    Af
    Bog E-bog
    • Format
    • Bog, hardback
    • Engelsk

    Beskrivelse

    This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

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    Detaljer
    • SprogEngelsk
    • Sidetal240
    • Udgivelsesdato31-08-1986
    • ISBN139780849357756
    • Forlag CRC Press Inc
    • FormatHardback
    Størrelse og vægt
  • Vægt793 g
    • coffee cup img
    10 cm
    book img
    21 cm
    28 cm

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    Pharmacokinetics Neurotoxic agents DNA modification Organic anions GSH peroxidase White Cells Bile Flow Biliary Excretion Compound Action Potential conduction velocity Blood Concentrations Cholestatic Damage Foreign Compounds GSSG Reductase Epoxide Hydrolase metabolic activation Mol Wt Hepatic Clearance Plasma Concentration Pyrrolic Metabolites Isonicotinic Acid Hydrazide reactive metabolites target organ toxicity Intrinsic Clearance Target Organ Susceptibility pharma-cologists Motor Nerve Terminal Relative Refractory Period
    Machine Name: SAXO083