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Epigenetics and Systems Biology

  • Format
  • Bog, hardback
  • Engelsk

Beskrivelse

Epigenetics and Systems Biology highlights the need for collaboration between experiments and theoretical modeling that is required for successful application of systems biology in epigenetics studies. This book breaks down the obstacles which exist between systems biology and epigenetics researchers due to information barriers and segmented research, giving real-life examples of successful combinations of systems biology and epigenetics experiments. Each section covers one type of modeling and one set of epigenetic questions on which said models have been successfully applied. In addition, the book highlights how modeling and systems biology relate to studies of RNA, DNA, and genome instability, mechanisms of DNA damage signaling and repair, and the effect of the environment on genome stability.

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Detaljer
  • SprogEngelsk
  • Sidetal286
  • Udgivelsesdato27-04-2017
  • ISBN139780128030752
  • Forlag Academic Press Inc
  • FormatHardback
Størrelse og vægt
  • Vægt810 g
  • coffee cup img
    10 cm
    book img
    19,1 cm
    23,5 cm

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    DNA Training Fluorescence in situ hybridization Machine learning Modeling Drosophila Chromatin Microscopy Arabidopsis thaliana DNA Methylation Simulation Ordinary differential equations Epigenetics Hidden Markov models Stochastic Simulation Local-Global Distributive Epigenetic memory Monte-Carlo-Simulation Kinetic modeling Live cell imaging Fluorescence correlation spectroscopy Integrative Modeling Domain Boundary TAD Dynamical systems, Profiling Partial correlation Cooperativity Genome Organization Pré Polymer Physics Yeast genome Super-resolution imaging Chromatin structure Chromosome structure Histone modification Transcriptional regulation Methyltransferase Switch Bistability Computer simulations Chromatin interactions Network reconstruction Histone methylation ChIP Mathematical modeling, ChIP-Seq Unsupervised learning Gene regulation Motifs Genome-wide Live imaging Polycomb Chromosome organization CPG Positive feedback Temperature sensing Nucleosome Heterochromatin Chromatin modifier Chromosome biophysics Chromosome conformation capture (3C) Chromosome conformation capture Chromatin classification Euchromatin chromatin signaling Chromosome/DNA dynamics Demethylase Chromatin/DNA labeling Chromosome compaction Chromosome flexibility Flowering Locus C Classifier performance High-throughput 3D imaging Fluorescence recovery after photobleaching H3K76 Dot1 E-value Methylomes Hi-C H3K79 Processive Quantitative epigenetics Nuclear compartment Polycomb response element Trithorax Single-nucleosome imaging vernalization
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