Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A

Hypnosis Crystallography Genetics Hysteresis Mass spectrometry Molecular dynamics. Electroencephalography Mutagenesis Anesthetics Electrophysiology Animal models Electromyography Behavior Anesthesia Docking Transfection Hippocampus NMR Pharmacokinetic Synaptic Transmission Computational chemistry Protein Zebrafish Ligand-Gated Ion Channels Human Neuroprotection Patch clamp NMDA receptor Computerized tomography Diazirine Genome editing Spectroscopy Free energy calculations Volatile anesthetics Covalent modification Model organisms Photoaffinity labeling Molecular modeling Kinetic model Cultured cells Voltage Clamping Heterologous expression Field Recording Molecular Mechanics Tadpole Sedation Bioassay Hyperpolarization Allosteric Modulation Parameterization Pharmacophore Behavioral assays Patch clamping Xenon Force field Pharmacodynamic Propofol Anesthetic Metadynamics Cysteine Anesthesia binding site Anesthetic analogs Anesthetic endpoints Anesthetic molecules Behavioral responsiveness Anesthetic mechanisms Binding site discovery Drosophila neuromuscular junction Forward genetic screens Gating modulation GABAA Receptor Interference RNA Dissociated neuron HEK293 Cell LGIC K2P channel Focal macropatch recording Ligand-gated ion channel Ligand-receptor interactions General anesthetic general anesthetics Nav channel Nicotinic acetylcholine receptor Pentameric channel Hyper-CEST ONIOM Pop spike Randomized clinical trial HCN channel sevoflurane Homology model Targeted genetic screens Voltage-gated ion channels Kv channel Membrane adsorption X. laevis Photolabel Optoanesthesia Two-electrode voltage clamp Phosphatidylcholine Xenopus oocyte